The mouthwash Colgate Periogard Plus is clinically proven to reduce the pathogenic bacteria responsible for gum bleeding. Mouthwash for daily use. Contains 0.05% Chloride Aketylopyridinio. Reduces pathogenic oral bacteria. Protects against tooth plaque and gum bleeding. Reduces plaque by 50% in areas of difficult access to five days. Actual activity after 24 weeks use. Clinically proven efficacy.